Table 3.

Effect of starting age, ending age and PSA threshold, and frequency on cost-effectiveness

Screening strategy	ICER ($/LYG)
Decreasing starting age
60(2)74	--
55(2)74	$27,600
50(2)74	$80,900
40(2)74	$494,000
Increasing ending age & threshold
50(2)69	--
50(2)74,4.0	dominated*
50(2)74	$48,100
Increasing frequency
50(4)74	--
50(A)74	$68,500
50(2)74	$1,150,000

Abbreviations: LYG, life-years gained; ICER, incremental cost-effectiveness ratio; see Table 2 for full screening strategy descriptions

^*Dominated strategies have a higher ICER (i.e., they are less cost-effective) than the next most effective strategy