Table 7.
Studies included in meta-analysis of the effect of DCS on the proportion of patients meeting remission status criteria at posttreatment
| First author | DCS group
|
Placebo group
|
Notes | ||||
|---|---|---|---|---|---|---|---|
| Remission (N) | Not remission (N) | Total (N) | Remission (N) | Not remission (N) | Total (N) | ||
| Storch 20078 | 5 | 7 | 12 | 7 | 5 | 12 | Remission defined as having a severity rating on the ADIS-IV ≤3 and CY-BOCS total score ≤10 assessed at 1-week posttreatment |
| Farrell 201318 | 5 | 4 | 9 | 4 | 4 | 8 | Remission defined by >50% reduction on the CY-BOCS combined with a CY-BOCS score of <14) at posttreatment |
| Mataix-Cols 201420 | 7 | 6 | 13 | 6 | 8 | 14 | Remission defined as CY-BOCS scores ≤10 at posttreatment |
Abbreviations: ADIS-IV, ADIS for Diagnostic and Statistical Manual of Mental Disorders, fourth edition; DCS, D-cycloserine; CY-BOCS, Children’s Yale-Brown Obsessive Compulsive Scale.