Abstinence was confirmed by breath levels of carbon monoxide (intention to treat). Standard treatment indicates 8 weeks of patch treatment (n = 180); extended treatment, 24 weeks of patch treatment (n = 173); and maintenance treatment, 52 weeks of patch treatment (n = 172). According to a multivariate model for standard and extended vs maintenance treatment arms at week 24, the odds ratio (OR) was 1.70 (95%CI, 1.03-2.81; P = .04). According to a multivariate model for standard and extended treatment vs maintenance treatment at week 52, the OR was 1.17 (95%CI, 0.69-1.98; P = .57).