Table 1.
a: Differentially Expressed MicroRNAs for all patients (Ulcerative colitis and Crohn’s disease) | ||||
---|---|---|---|---|
Dysregulated microRNA |
p-value* | Fold Change Non-neoplasia to Dysplasia |
Fold Change Non-neoplasia to Cancer |
Fold Change Dysplasia to Cancer |
miR-193b | 0.0016 | −1.29 | −1.98 | −1.54 |
miR-373 | 0.0009 | −1.28 | −2.00 | −1.56 |
let-7e | 0.0001 | −1.16 | −1.87 | −1.61 |
miR-15b | 0.0012 | −1.17 | −1.89 | −1.62 |
miR-372 | 0.0018 | −1.20 | −1.96 | −1.63 |
b: Differentially Expressed MicroRNAs (DEMs) for Crohn’s disease patients | ||||
---|---|---|---|---|
Dysregulated microRNA |
p-value* | Fold Change Non-neoplasia to Dysplasia |
Fold Change Non-neoplasia to Cancer |
Fold Change Dysplasia to Cancer |
miR-122 | 0.0009 | +2.05 | −1.68 | −3.85 |
miR-181a | 0.0011 | +2.25 | −1.69 | −3.80 |
miR-146b-5p | 0.0031 | +2.00 | −1.65 | −3.31 |
let-7e | 0.0003 | +2.29 | −1.52 | −3.49 |
miR-17 | 0.0052 | +2.22 | −1.61 | −3.56 |
miR-143 | 0.0024 | +2.03 | −1.74 | −3.53 |
Global p-value calculated for any difference in miRNA dysregulation in the cohort. This p-value was calculated at a False Discovery Rate (FDR) <10%