Table 2.
Disease characteristics and medication use in the RA patients with carotid plaque compared to the RA patients without carotid plaque*
Patients with plaque (n = 72) | Patients without plaque (n = 96) | P | |
---|---|---|---|
No. of tender joints (28-joint count) | 8±8 | 8±8 | 0.76 |
No. of swollen joints (28-joint count) | 4 ± 5 | 4 ± 5 | 0.54 |
DAS28 | 4.4 ± 1.8 | 4.3 ± 2.0 | 0.75 |
Patient's assessment of pain, 0–100-mm VAS | 39 ± 29 | 41 ± 31 | 0.60 |
Patient's global assessment of disease activity, 0–100-mm VAS | 42 ± 29 | 42 ± 31 | 0.79 |
Physician's global assessment of disease activity, 0–100-mm VAS | 35 ± 21 | 40 ± 27 | 0.45 |
Patient's assessment of stiffness, 0–100-mm VAS | 35 ± 29 | 38 ± 29 | 0.60 |
Patient's assessment of fatigue, 0–100-mm VAS | 45 ± 29 | 42 ± 27 | 0.51 |
HAQ DI score | 1.0 ± 0.79 | 0.97 ± 0.87 | 0.72 |
Medication use, % | |||
Cholesterol-lowering drugs | 36 | 13 | 0.0006 |
NSAIDs | 36 | 30 | 0.50 |
Prednisone | 36 | 19 | 0.02 |
Methotrexate | 54 | 60 | 0.52 |
Leflunomide | 8 | 12 | 0.61 |
Hydroxychloroquine | 17 | 18 | 0.84 |
TNFα inhibitors | 43 | 40 | 0.75 |
Other biologic agents | 13 | 9 | 0.45 |
Except where indicated otherwise, values are the mean ± SD. RA = rheumatoid arthritis; DAS28 = Disease Activity Score in 28 joints; VAS = visual analog scale; HAQ DI = Health Assessment Questionnaire disability index; NSAIDs = nonsteroidal antiinflammatory drugs; TNFα = tumor necrosis factor α.