Table 3.
Multivariate analysis of the association between prognosis and lymph node status in patients with esophageal cancer
| Characteristic | All patients
|
Lymph node-negative
|
||||
|---|---|---|---|---|---|---|
| HR | 95% CI | P | HR | 95% CI | P | |
| Sex | ||||||
| Male | 1 | – | ||||
| Female | 0.634 | 0.483–0.832 | 0.001 | – | – | – |
| Tumor stage | ||||||
| pT1-2 | 1 | – | ||||
| pT3 | 1.227 | 0.951–1.583 | 0.116 | – | – | – |
| Node stage | ||||||
| pN0 | 1 | – | ||||
| pN1 | 2.025 | 1.558–2.632 | <0.001 | – | – | – |
| pN2 | 3.262 | 2.449–4.344 | <0.001 | – | – | – |
| pN3 | 8.873 | 5.480–14.366 | <0.001 | – | – | – |
| Histological grade | ||||||
| G1 | 1 | 1 | ||||
| G2 | 1.222 | 0.884–1.688 | 0.225 | 1.545 | 0.951–2.508 | 0.079 |
| G3 | 1.417 | 1.009–1.990 | 0.044 | 2.066 | 1.234–3.457 | 0.006 |
| ABO blood group | ||||||
| Non-AB | 1 | 1 | ||||
| AB | 1.007 | 0.765–1.505 | 0.972 | 2.576 | 1.349–4.919 | 0.004 |
| Smoking | ||||||
| Never | 1 | – | ||||
| Ever | 1.073 | 0.765–1.505 | 0.685 | – | – | – |
| Alcohol consumption | ||||||
| No | 1 | 1 | ||||
| Yes | 1.620 | 1.264–2.076 | <0.001 | 1.681 | 1.151–2.464 | 0.007 |
Abbreviations: CI, confidence interval; G, grade; HR, hazard ratio; N, node; p, primary; T, tumor.