Figure S7.
TSS Escaping Indexes and CLIP Analysis, Related to Figure 7
(A) EI and normalized GB profiles of each mNET-seq (right). GB signals were divided by signals in promoter region (PRO, −50 to +250 bp over TSS) for EI. The EI (n = 1,974) and normalized GB (n = 1,974) with indicated Pol II antibodies and siRNA treatments are shown below. (∗∗∗) p value < 8.4 × 10−48, (∗∗) p value < 6.7 × 10−20 and (∗) p value < 4.5 × 10−4 by two-sided Mann-Whitney test; (ns) indicates no difference between samples (p value > 0.001 by two-sided Mann-Whitney test).
(B) The EI (left, n = 2,106) and normalized GB (right, n = 1,974) with indicated siRNA treatments are shown below. (∗∗∗) p value < 1.3 × 10−63 by two-sided Mann-Whitney test; (ns) indicates no difference between samples (p value > 0.001 by two-sided Mann-Whitney test).
(C) CLIP analysis of TSS associated CPA factors (Martin et al., 2012). Normalized read counts and distance from TSS are shown at y and x axes. Sense, blue; antisense, red.