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Viruses investigated as etiological agents in Sjögren’s syndrome. The plus (+) signs indicate research that given virus has been implicated in the one of the molecular pathogenic mechanisms shown. A negative sign (−) indicates there is no evidence for a virus with the given mechanisms.
| Pathogenic Mechanisms | |||
|---|---|---|---|
| Molecular mimicry | Polyclonal activation | Inflammation | |
| EBV | + | − | + |
| CMV | + | − | + |
| Parovirus B19 | − | − | − |
| HBV | + | − | − |
| HCV | − | + | + |
| Coxackie | + | − | + |
| HTLV1 | − | − | + |
