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. Author manuscript; available in PMC: 2016 Apr 3.
Published in final edited form as: J Proteome Res. 2015 Mar 9;14(4):1968–1978. doi: 10.1021/acs.jproteome.5b00068

Table 3. CF Peptides Presented in Significantly Different Levels between Pancreatic Cancer and Chronic Pancreatitisa.

accession no. protein name CF peptideb N/SR CP/SR PC/SR
P54289 Voltage-dependent calcium channel
 subunit alpha-2/delta-1
DDLDPEKn*DSEPGSQR 1.13 ± 1.01 1.16 ± 0.42 0.70 ± 0.15d
Q9BXJ4 Complement C1q tumor necrosis
 factor
TGTVDn*NTSTDLK 9.88 ± 0.42 1.45 ± 0.55c 0.83 ± 0.25d
Q12913 Receptor-type tyrosine-protein
 phosphatase eta
Sn*DTAASEYK 0.85 ± 0.25 1.26 ± 0.26c 0.85 ± 0.26d
P01023 Alpha-2-macroglobulin GNEANYYSn*ATTDEHGLVQFSIn*TTNVMGTSLTVR 1.14 ± 0.49 1.88 ± 0.34c 1.04 ± 0.39d
Q7Z7G0 Target of Nesh-SH3 En*GSFSGK 0.80 ± 0.27 1.24 ± 0.20c 0.85 ± 0.19d
P16112 Aggrecan TVYLYPn*QTGLPDPLSR 0.91 ± 0.29 1.25 ± 0.39 0.83 ± 0.14d
P58215 Lysyl oxidase homologue 3 n*ITAEDCSHSQDAGVR 0.88 ± 0.41 0.75 ± 0.30 1.19 ± 0.19d
P12111 Collagen alpha-3(VI) chain VAVVQHAPSESVDn*ASMPPVK 0.93 ± 0.24 1.34 ± 0.31c 0.99 ± 0.20d
P20023 Complement receptor type 2 TPNGn*HTGGNIAR 0.87 ± 0.30 1.10 ± 0.30c 0.57 ± 0.34d
P13591 Neural cell adhesion
 molecule 1
n*ISSEEK 1.05 ± 0.43 1.26 ± 0.44c 0.89 ± 0.32d
Q13477 Mucosal addressin cell adhesion molecule 1 n*ASLSAAGTR 1.13 ± 0.50 1.76 ± 0.72c 0.94 ± 0.20d
P14151 L-selectin IGGIWTWVGTn*K(SL) 1.09 ± 0.41 1.15 ± 0.27c 0.90 ± 0.29d
P01011 Alpha-1-antichymotrypsin LINDYVKn*GTR 0.53 ± 0.38 1.41 ± 0.64c 0.91 ± 0.39cd
a

Data represent the mean and SD value based on the reporter ion ratios for CF proteins quantified in at least 5 sample sets. Significant difference level P ≤ 0.05; N, healthy controls; CP, chronic pancreatitis; PC, pancreatic cancer; SR, standard reference.

b

Asterisk (*) indicates CF modification at asparagine (n) residue.

c

Difference between healthy controls and pancreatic cancer or chronic pancreatitis.

d

Difference between pancreatic cancer and chronic pancreatitis.