Table 4. Occurrence of individual adverse events.

Adverse events (n)	Grade 0	Grade 1	Grade 2	Grade 3
Alopecia	16 (34.0%)	12 (25.5%)	19 (40.4%)	0 (0%)
Nail ridging	42 (89.4%)	5 (10.5%)	0 (0%)	0 0%)
Dry skin	40 (85.1%)	7 (14.9%)	0 (0%)	0 (0%)
Nausea	35 (74.5%)	9 (19.1%)	3 (6.4%)	0 (0%)
Constipation	31 (66.0%)	12 (25.5%)	3 (6.4%)	1 (2.1%)
Mucositis oral	35 (74.5%)	10 (21.3%)	2 (4.3%)	0 (0%)
Oral pain	42 (89.4%)	5 (10.6%)	0 (0%)	0 0%)
Peripheral sensory neuropathy	38 (80.9%)	9 (19.1%)	0 (0%)	0 (0%)
Dysgeusia	39 (83.0%)	3 (6.4%)	5 (10.6%)	0 (0%)
Malaise	21 (44.7%)	19 (40.4%)	7 (14.9%)	0 0%)
Fever	40 (85.1%)	7 (14.9%)	0 (0%)	0 (0%)
White blood cell decreased	37 (78.7%)	8 (17.0%)	2 (4.3%)	0 (0%)
Anemia	29 (61.7%)	18 (38.3%)	0 (0%)	0 0%)
Anorexia	27 (57.4%)	9 (19.1%)	11 (23.4%)	0 (0%)