Table 5. Comparison of the EQ-5D utility value according to the presence or absence of individual adverse events.

Adverse events			Utility value
	Grade	N	Before CT (A)	After CT (B)	Difference (B-A)	p
Alopecia						0.224
	0	16	0.83±0.19	0.76±0.18	-0.07±0.14
	1–3	31	0.84±0.15	0.71±0.19	-0.13±0.18
Nail ridging						0.541
	0	42	0.84±0.17	0.73±0.19	-0.11±0.17
	1–3	5	0.84±0.15	0.68±0.15	-0.16±0.15
Dry skin						0.802
	0	40	0.85±0.16	0.74±0.18	-0.11±0.18
	1–3	7	0.76±0.20	0.64±0.16	-0.13±0.13
Nausea						0.646
	0	35	0.83±0.17	0.72±0.20	-0.10±0.18
	1–3	12	0.87±0.16	0.74±0.12	-0.13±0.14
Constipation						0.239
	0	31	0.85±0.14	0.76±0.14	-0.09±0.16
	1–3	16	0.82±0.15	0.67±0.24	-0.15±0.18
Mucositis oral						0.237
	0	35	0.84±0.16	0.74±0.19	-0.09±0.18
	1–3	12	0.84±0.19	0.68±0.17	-0.16±0.14
Oral pain						0.927
	0	42	0.85±0.17	0.74±0.19	-0.11±0.18
	1–3	5	0.78±0.13	0.66±0.15	-0.12±0.12
Peripheral sensory neuropathy						0.628
	0	38	0.86±0.15	0.74±0.18	-0.12±0.18
	1–3	9	0.76±0.21	0.67±0.18	-0.08±0.15
Dysgeusia						0.705
	0	39	0.83±0.17	0.72±0.19	-0.12±0.18
	1–3	8	0.86±0.15	0.77±0.12	-0.09±0.10
Malaise						0.643
	0	21	0.87±0.16	0.78±0.14	-0.10±0.14
	1–3	26	0.81±0.17	0.69±0.21	-0.12±0.19
Fever						0.884
	0	40	0.85±0.16	0.74±0.19	-0.11±0.18
	1–3	7	0.81±0.19	0.69±0.13	-0.12±0.12
White blood cell decreased						0.059
	0	37	0.84±0.17	0.71±0.19	-0.14±0.17
	1–3	10	0.83±0.15	0.81±0.14	-0.02±0.16
Anemia						0.694
	0	29	0.86±0.17	0.74±0.16	-0.12±0.15
	1–3	18	0.80±0.16	0.70±0.22	-0.10±0.21
Anorexia						0.009*
	0	27	0.82±0.17	0.77±0.16	-0.06±0.16
	1–3	20	0.86±0.16	0.68±0.21	-0.19±0.16

CT: chemotherapy, mean±standard deviation,

*p<0.05