Table 6. Comparison of 5 dimensions according to the presence or absence of individual adverse events.
| Adverse events | Mobility | Personal care | Usual activities | Pain/discomfort | Anxiety/depression | |||||||||||||||||
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| Grade | n | Some or major problems (%) | Deteriorated (%) | p | Some or major problems (%) | Deteriorated (%) | p | Some or major problems (%) | Deteriorated (%) | p | Some or major problems (%) | Deteriorated (%) | p | Some or major problems (%) | Deteriorated (%) | p | ||||||
| Before CT | After CT | Before CT | After CT | Before CT | After CT | Before CT | After CT | Before CT | After CT | |||||||||||||
| Alopecia | 1.000 | 1.000 | 0.008* | 0.036* | 0.739 | |||||||||||||||||
| 0 | 16 | 18.8 | 37.5 | 18.8 | 12.5 | 18.8 | 6.3 | 18.8 | 25.0 | 6.3 | 43.8 | 37.5 | 6.3 | 31.3 | 56.3 | 31.3 | ||||||
| 1–3 | 31 | 6.5 | 25.8 | 19.4 | 3.2 | 9.7 | 6.5 | 6.5 | 45.2 | 45.2 | 41.9 | 58.1 | 38.7 | 45.2 | 51.6 | 25.8 | ||||||
| Nail ridging | 1.000 | 0.292 | 0.648 | 0.607 | 1.000 | |||||||||||||||||
| 0 | 42 | 11.9 | 31.0 | 19.0 | 7.1 | 11.9 | 4.8 | 11.9 | 38.1 | 31.0 | 40.5 | 47.6 | 26.2 | 40.5 | 52.4 | 28.6 | ||||||
| 1–3 | 5 | 0.0 | 20.0 | 20.0 | 0.0 | 20.0 | 20.0 | 0.0 | 40.0 | 40.0 | 60.0 | 80.0 | 40.0 | 40.00 | 60.00 | 20.0 | ||||||
| Dry skin | 0.605 | 0.391 | 1.000 | 0.377 | 1.000 | |||||||||||||||||
| 0 | 40 | 10.0 | 27.5 | 17.5 | 5.0 | 10.0 | 5.00 | 10.0 | 37.5 | 32.5 | 40.0 | 45.0 | 25.0 | 37.5 | 50.0 | 27.5 | ||||||
| 1–3 | 7 | 14.3 | 42.9 | 28.6 | 14.3 | 28.6 | 14.3 | 14.3 | 42.9 | 28.6 | 57.1 | 85.7 | 42.9 | 57.14 | 71.43 | 28.6 | ||||||
| Nausea | 0.412 | 0.560 | 0.158 | 1.000 | 0.269 | |||||||||||||||||
| 0 | 35 | 11.4 | 34.3 | 22.9 | 8.6 | 17.1 | 8.6 | 11.4 | 34.3 | 25.7 | 42.9 | 54.3 | 28.6 | 42.9 | 48.6 | 22.9 | ||||||
| 1–3 | 12 | 8.3 | 16.8 | 8.3 | 0.0 | 0.0 | 0.0 | 8.3 | 50.0 | 50.0 | 41.67 | 41.67 | 25.0 | 33.33 | 66.67 | 41.7 | ||||||
| Constipation | 0.466 | 0.264 | 0.019* | 0.096 | 0.168 | |||||||||||||||||
| 0 | 31 | 12.9 | 29.0 | 16.1 | 6.5 | 9.7 | 3.2 | 16.1 | 29.0 | 19.4 | 41.9 | 41.9 | 19.4 | 32.3 | 61.3 | 35.5 | ||||||
| 1–3 | 16 | 6.3 | 31.3 | 25.0 | 6.3 | 18.8 | 12.5 | 0.0 | 56.3 | 56.3 | 43.8 | 68.8 | 43.8 | 56.3 | 37.5 | 12.5 | ||||||
| Mucositis oral | 0.205 | 0.560 | 1.000 | 0.065 | 0.713 | |||||||||||||||||
| 0 | 35 | 11.4 | 25.7 | 14.3 | 5.7 | 14.3 | 8.6 | 11.4 | 37.1 | 31.4 | 48.6 | 45.7 | 20.0 | 37.1 | 48.6 | 25.7 | ||||||
| 1–3 | 12 | 8.3 | 41.6 | 33.3 | 8.3 | 8.3 | 0.0 | 8.3 | 41.7 | 33.3 | 25.0 | 66.7 | 50.0 | 50.0 | 66.7 | 33.3 | ||||||
| Oral pain | 1.000 | 0.292 | 0.309 | 0.607 | 0.607 | |||||||||||||||||
| 0 | 42 | 9.5 | 28.6 | 19.0 | 7.1 | 11.9 | 4.8 | 11.9 | 35.7 | 28.6 | 40.5 | 50.0 | 26.2 | 38.1 | 50.0 | 26.2 | ||||||
| 1–3 | 5 | 20.0 | 40.0 | 20.0 | 0.0 | 20.0 | 20.0 | 0.0 | 60.0 | 60.0 | 60.0 | 60.0 | 40.0 | 60.0 | 80.0 | 40.0 | ||||||
| Peripheral sensory neuropathy | 1.000 | 1.000 | 1.000 | 0.692 | 1.000 | |||||||||||||||||
| 0 | 38 | 5.3 | 23.7 | 18.4 | 2.6 | 10.5 | 7.9 | 10.5 | 36.8 | 31.6 | 39.5 | 50.0 | 26.3 | 36.8 | 47.4 | 28.9 | ||||||
| 1–3 | 9 | 33.3 | 55.6 | 22.2 | 22.2 | 22.2 | 0.0 | 11.1 | 44.4 | 33.3 | 55.6 | 55.6 | 33.3 | 55.56 | 77.78 | 22.2 | ||||||
| Dysgeusia | 1.000 | 1.000 | 0.246 | 0.413 | 1.000 | |||||||||||||||||
| 0 | 39 | 12.8 | 33.3 | 20.5 | 7.7 | 15.4 | 7.7 | 12.8 | 35.9 | 28.2 | 43.6 | 53.8 | 30.8 | 41.0 | 53.8 | 28.2 | ||||||
| 1–3 | 8 | 0.0 | 12.5 | 12.5 | 0.0 | 0.0 | 0.0 | 0.0 | 50.0 | 50.0 | 37.5 | 37.5 | 12.5 | 37.5 | 50.0 | 25.0 | ||||||
| Malaise | 0.711 | 1.000 | 0.028* | 0.744 | 0.746 | |||||||||||||||||
| 0 | 21 | 9.5 | 23.8 | 14.3 | 4.8 | 9.5 | 4.8 | 14.3 | 23.8 | 14.3 | 33.3 | 47.6 | 28.6 | 28.6 | 38.1 | 23.8 | ||||||
| 1–3 | 26 | 11.5 | 34.6 | 23.1 | 7.7 | 15.4 | 7.7 | 7.7 | 50.0 | 46.2 | 50.0 | 53.9 | 23.1 | 50.0 | 65.4 | 30.8 | ||||||
| Fever | 0.318 | 1.000 | 0.188 | 1.000 | 1.000 | |||||||||||||||||
| 0 | 40 | 10.0 | 32.5 | 22.5 | 5.0 | 12.5 | 7.5 | 12.5 | 35.0 | 27.5 | 40.0 | 47.5 | 27.5 | 37.5 | 50.0 | 27.5 | ||||||
| 1–3 | 7 | 14.3 | 14.3 | 0.0 | 14.3 | 14.3 | 0.0 | 0.0 | 57.1 | 57.1 | 57.1 | 71.4 | 28.6 | 57.1 | 71.4 | 28.6 | ||||||
| White blood cell decreased | 1.000 | 1.000 | 0.465 | 0.703 | 1.000 | |||||||||||||||||
| 0 | 37 | 13.5 | 32.4 | 18.9 | 8.1 | 16.2 | 8.1 | 10.8 | 43.2 | 35.1 | 40.5 | 54.1 | 29.7 | 40.5 | 56.8 | 27.0 | ||||||
| 1–3 | 10 | 0.0 | 20.0 | 20.0 | 0.00 | 0.00 | 0.0 | 10.0 | 20.0 | 20.0 | 50.0 | 40.0 | 20.0 | 40.0 | 40.0 | 20.0 | ||||||
| Anemia | 0.716 | 1.000 | 0.202 | 1.000 | 0.315 | |||||||||||||||||
| 0 | 29 | 13.8 | 31.0 | 17.2 | 6.9 | 13.8 | 6.9 | 10.3 | 34.5 | 24.1 | 34.5 | 48.3 | 27.6 | 31.0 | 55.2 | 34.5 | ||||||
| 1–3 | 18 | 5.6 | 27.8 | 22.2 | 5.6 | 11.1 | 5.6 | 11.1 | 44.4 | 44.4 | 55.6 | 55.6 | 27.8 | 55.6 | 50.0 | 16.7 | ||||||
| Anorexia | 0.142 | 0.567 | 0.030* | 1.000 | 0.511 | |||||||||||||||||
| 0 | 27 | 14.8 | 25.9 | 11.1 | 7.4 | 11.1 | 3.7 | 18.5 | 29.6 | 18.5 | 44.4 | 55.6 | 25.9 | 40.7 | 40.7 | 22.2 | ||||||
| 1–3 | 20 | 5.0 | 35.0 | 30.0 | 5.0 | 15.0 | 10.0 | 0.0 | 50.0 | 50.0 | 40.0 | 45.0 | 30.0 | 40.0 | 70.0 | 35.0 | ||||||
CT: chemotherapy,
*p<0.05