Table 7. Comparison of the QOL-ACD total score for each subscale according to the presence or absence of individual adverse events.

Adverse events	Grade	n	Total score
			Before CT (A)	After CT (B)	Difference (B-A)	p
Alopecia						0.649
	0	16	86.25±13.91	83.31±16.20	-2.94±11.01
	1–3	31	89.74±9.40	85.23±12.96	-4.52±11.28
Nail ridging						0.671
	0	42	88.17±11.48	84.43±14.27	-3.74±11.40
	1–3	5	91.80±7.43	85.80±12.85	-6.00±8.80
Dry skin						0.795
	0	40	88.83±10.89	85.03±14.19	-3.80±11.85
	1–3	7	87.00±13.14	82.00±13.60	-5.00±5.35
Nausea						0.123
	0	35	87.63±10.88	85.11±15.08	-2.51±11.82
	1–3	12	91.25±11.84	83.00±10.62	-8.25±7.48
Constipation						0.675
	0	31	89.26±12.55	85.77±13.65	-3.48±10.02
	1–3	16	87.19±7.78	82.25±14.82	-4.94±13.23
Mucositis oral						0.885
	0	35	88.54±10.60	84.46±14.38	-4.09±12.30
	1–3	12	88.58±13.01	84.92±13.43	-3.67±6.84
Oral pain						0.309
	0	42	88.62±11.36	85.21±14.09	-3.41±11.52
	1–3	5	88.00±9.82	79.20±13.37	-8.80±4.82
Peripheral sensory neuropathy						0.376
	0	38	89.13±11.53	84.45±13.88	-4.68±11.05
	1–3	9	86.11±9.36	85.11±15.34	-1.00±11.42
Dysgeusia						0.123
	0	39	87.54±11.42	84.69±14.97	-2.85±11.49
	1–3	8	93.50±8.37	84.00±8.45	-9.50±7.03
Malaise						0.456
	0	21	89.10±12.91	86.48±14.74	-2.62±9.99
	1–3	26	88.12±9.67	83.04±13.46	-5.08±11.99
Fever						0.075
	0	40	87.48±11.39	84.70±14.34	-2.78±10.98
	1–3	7	94.71±7.16	83.86±12.82	-10.86±9.75
White blood cell decreased						0.229
	0	37	88.81±11.84	83.81±15.23	-5.00±11.22
	1–3	10	87.60±8.32	87.40±7.95	-0.20±10.26
Anemia						0.481
	0	29	89.10±11.75	86.03±14.64	-3.07±10.69
	1–3	18	87.67±10.26	82.22±12.95	-5.44±11.87
Anorexia						<0.001 *
	0	27	86.40±11.76	87.48±14.65	1.07±10.25
	1–3	20	91.45±9.71	80.65±12.35	-10.80±8.29

CT: chemotherapy, mean±standard deviation,

*p<0.05