Table 1. Participant characteristics by quartiles of serum triglycerides concentration (n = 10,808) a .
| Quartiles of serum triglycerides concentration (range, mmol/L) | |||||
|---|---|---|---|---|---|
| Males | Level 1 (0.32–1.14) | Level 2 (1.15–1.63) | Level 3 (1.64–2.37) | Level 4 (2.38–28.35) | P for trend b |
| (n = 1,635) | (n = 1,621) | (n = 1,595) | (n = 1,619) | ||
| Age (y) | 45.3 (38.0, 55.0) c | 46.3 (40.0, 54.0) d | 46.0 (40.0, 53.0) d | 45.0 (39.0, 51.0) | 0.0012 |
| BMI (kg/m 2 ) | 24.5 (22.5, 26.8) d | 25.7 (23.8, 28) d | 26.4 (24.7, 28.5) d | 27.1 (25.3, 29.1) | < 0.0001 |
| Waist circumference (cm) | 86.0 (80.0, 92.0) d | 90.0 (84.0, 96.0) d | 92.0 (87.0, 97.0) d | 94.0 (89.0, 99.0) | < 0.0001 |
| TC (mmol/L) | 4.74 (4.21, 5.30) d | 5.10 (4.56, 5.67) d | 5.30 (4.78, 5.90) d | 5.54 (4.92, 6.21) | < 0.0001 |
| LDL (mmol/L) | 2.90 (2.45, 3.40) d | 3.18 (2.70, 3.69) d | 3.21 (2.70, 3.75) d | 3.12 (2.46, 3.70) | < 0.0001 |
| HDL (mmol/L) | 1.40 (1.21, 1.63) d | 1.27 (1.09, 1.46) d | 1.19 (1.03, 1.37) d | 1.06 (0.92, 1.24) | < 0.0001 |
| SBP (mmHg) | 120 (110, 135) d | 125 (115, 135) d | 125 (115, 135) d | 130 (120, 140) | < 0.0001 |
| DBP (mmHg) | 80 (70, 85) d | 80 (75, 90) d | 85 (75, 90) d | 85 (80, 95) | < 0.0001 |
| FBS (mmol/L) | 4.9 (4.5, 5.3) d | 5.1 (4.6, 5.6) d | 5.1 (4.7, 5.6) d | 5.3 (4.9, 5.9) | < 0.0001 |
| ALB (g/L) | 46 (44, 48) d | 47 (45, 49) | 47 (45, 49) | 47 (45, 49) | < 0.0001 |
| SCr (μmol/L) | 77 (70, 85) d | 78 (71, 85) | 79 (72, 86) | 78 (71, 85) | < 0.0001 |
| IgM (mg/dl) | 79.1 (58.4, 107.0) d | 81.9 (59.5, 111.0) | 80.4 (59.0, 108.0) d | 83.7 (61.6, 113.0) | 0.71 |
| Hypertension (%) | 27.7 | 34.7 | 38.1 | 45.3 | < 0.0001 |
| Diabetes (%) | 7.2 | 10.0 | 10.7 | 14.9 | < 0.0001 |
| Smoking status (%) | |||||
| Smoker | 40.6 | 49.3 | 49.5 | 55.6 | < 0.0001 |
| Ex-smoker | 0.31 | 0.12 | 0.31 | 0.06 | 0.25 |
| Drinker (%) | 60.1 | 65.4 | 68.8 | 76.3 | < 0.0001 |
| Family history of diseases (%) | |||||
| CVD | 29.4 | 33.6 | 32.5 | 33.2 | 0.07 |
| Hypertension | 43.6 | 46.8 | 47.6 | 50.2 | < 0.001 |
| Hyperlipidemia | 0.31 | 0.25 | 0.25 | 0.43 | 0.44 |
| Diabetes | 16.2 | 19.4 | 20.6 | 21.9 | < 0.001 |
| Females | Level 1 (0.32–0.78) | Level 2 (0.79–1.09) | Level 3 (1.10–1.58) | Level 4 (1.59–23.74) | |
| (n = 1,102) | (n = 1,079) | (n = 1,071) | (n = 1,086) | ||
| Age (y) | 40.0 (35.0, 46.0) d | 46.0 (39.0, 53.0) d | 49.0 (41.0, 57.0) d | 52.0 (44.3, 60.0) | <0.0001 |
| BMI (kg/m 2 ) | 21.9 (20.3, 23.9) d | 23.3 (21.4, 25.4) d | 24.4 (22.4, 26.6) d | 25.8 (23.5, 28.2) | <0.0001 |
| Waist circumference (cm) | 73 (68, 79) d | 77 (72, 83) d | 80 (75, 87) d | 84 (79, 91) | <0.0001 |
| TC (mmol/L) | 4.66 (4.12, 5.21) d | 5.01 (4.45, 5.62) d | 5.25 (4.65, 5.97) d | 5.69 (5.11, 6.39) | <0.0001 |
| LDL (mmol/L) | 2.66 (2.22, 3.13) d | 2.98 (2.49, 3.51) d | 3.17 (2.67, 3.82) d | 3.39 (2.79, 4.04) | <0.0001 |
| HDL (mmol/L) | 1.71 (1.48, 1.96) d | 1.60 (1.39, 1.82) d | 1.45 (1.26, 1.68) d | 1.28 (1.09, 1.47) | <0.0001 |
| SBP (mmHg) | 110 (100, 120) d | 120 (110, 130) d | 125 (110, 135) d | 130 (115, 145) | <0.0001 |
| DBP (mmHg) | 70 (65, 80) d | 75 (65, 80) d | 75 (70, 85) d | 80 (70, 85) | <0.0001 |
| FBS (mmol/L) | 4.7 (4.4, 5.0) d | 4.8 (4.5, 5.2) d | 4.9 (4.6, 5.3) d | 5.1 (4.7, 5.6) | <0.0001 |
| ALB (g/L) | 46 (44, 48) d | 46 (44, 48) d | 46 (44, 48) d | 46 (44, 48) | 0.77 |
| SCr (μmol/L) | 57 (52, 64) d | 58 (53, 64) | 58 (53, 65) | 59 (54, 65) | 0.0016 |
| IgM (mg/dl) | 124.0 (89.7, 169.0) d | 115.0 (86.0, 157.0) d | 107.0 (79.5, 149.0) | 105.5 (75.3, 147.0) | <0.0001 |
| Hypertension (%) | 10.3 | 19.6 | 26.6 | 40.2 | <0.0001 |
| Diabetes (%) | 1.3 | 2.9 | 6.1 | 9.1 | <0.0001 |
| Smoking status (%) | |||||
| Smoker | 3.2 | 5.0 | 4.8 | 6.9 | <0.01 |
| Ex-smoker | |||||
| Drinker (%) | 16.0 | 16.0 | 14.7 | 12.8 | 0.02 |
| Family history of diseases (%) | |||||
| CVD | 29.4 | 39.5 | 33.2 | 34.9 | 0.1 |
| Hypertension | 47.9 | 51.3 | 45.9 | 45.5 | 0.04 |
| Hyperlipidemia | 0.5 | 0.3 | 0.7 | 0.1 | 0.32 |
| Diabetes | 18.6 | 19.4 | 20.4 | 19.4 | 0.68 |
a BMI, body mass index; TC, total cholesterol; TG, triglycerides; LDL, low density lipoprotein cholesterol; HDL, high-density lipoprotein-cholesterol; SBP, systolic blood pressure; DBP, diastolic blood pressure; FBS, fasting blood sugar; ALB, albumin; SCr, serum creatinine; IgM, immunoglobulin M; CVD, cardiovascular disease.
b Analysis of variance or logistic regression analysis.
c Median (interquartile range) (all such values).
d Significantly different from the forth quartile of triglycerides (Bonferroni correction): P < 0.05.