Fig 4. Deletion of the 55C Bom genes impairs resistance to E. faecalis infection rather than tolerance.

(A) Points indicate the mean CFU/fly from individual experiments using pools of 5–10 flies per genotype after E. faecalis infection at the indicated time point. Horizontal bars represent the means of the (four or more) independent experiments shown. Significance was measured by two-way ANOVA and is relative to the wild type (w ¹¹¹⁸) at the same time point (** p<0.01, *** p<0.001). (B) CFU of individual wild-type (w ¹¹¹⁸) flies at 44 hours post-infection. Horizontal bars represent means. “Low” (<3800 CFU/fly) and “high” (>3800 CFU/fly) populations were measured simultaneously during four independent collections of individual flies. Data were binned (indicated by boxes), and means were calculated separately.