Table 2. Demographic and disease characteristics of the patients.
| Parameters | All patients (n = 224) | Mild (n = 110) | Moderate (n = 114) | P value |
|---|---|---|---|---|
| Demographics | ||||
| Age (years) | 0.11 | |||
| Median (IQR) | 38.00(29.00–47.00) | 37.00(38.00–45.00) | 39.00(32.00–49.00) | |
| Range | 19–65 | 19–63 | 19–65 | |
| Gender, n (%) | 0.39 | |||
| Male | 130(58.0%) | 67(60.9%) | 63(55.3%) | |
| Female | 94(42.0%) | 43(39.1%) | 51(44.7%) | |
| Disease characteristics | ||||
| Disease distribution, n (%) | 0.04 | |||
| Proctitis | 89(39.7%) | 50(45.5%) | 39(34.2%) | |
| Left-sided | 87(38.8%) | 44(40.0%) | 43(37.7%) | |
| Extensive | 48(21.5%) | 16(14.5%) | 32(28.1%) | |
| Endoscopic grade, n (%) | 0.00 | |||
| Mild findings on endoscopy | 56(25.0%) | 47(42.7%) | 9(7.9%) | |
| Moderate findings on endoscopy | 97(43.3%) | 31(28.2%) | 66(57.9%) | |
| Severe findings on endoscopy | 71(31.7%) | 32(29.1%) | 39(34.2%) | |
| Extra-intestinal manifestations, n (%) | 3(1.3%) | 1(0.9%) | 2(1.8%) | 1.00 |
| Disease duration | 0.98 | |||
| <1 year | 36(16.1%) | 18(16.4%) | 18(15.8%) | |
| 1–5 years | 140(62.5%) | 68(61.8%) | 72(63.1%) | |
| >5 years | 48(21.4%) | 24(21.8%) | 24(21.1%) | |
| Range (years) | 0.5–30 | 0.5–30 | 0.5–20 | |
| Inpatient or outpatient, n (%) | 0.44 | |||
| Hospitalized | 21(9.4%) | 12(10.9%) | 9(7.9%) | |
| Outpatient | 203(90.6%) | 98(89.1%) | 105(92.1%) | |
| Laboratory examination | ||||
| Leukocytes (109/L) | 6.24±1.85 | 5.78±1.55 | 6.68±2.02 | 0.00 |
| Hemoglobin (g/L) | 134.03±20.24 | 135.32±19.74 | 132.78±20.71 | 0.35 |
| CRP (mg/L) | 5.26±5.09 a | 4.34±3.88 b | 6.10±5.89 c | 0.03 |
| Medications, n (%) | ||||
| 5-aminosalicylates | 89 | 53 | 36 | |
| 5-aminosalicylates+corticosteroids | 32 | 5 | 27 | |
| 5-aminosalicylates+azathioprine | 5 | 0 | 5 | |
| 5-aminosalicylates+Chinese herbs | 75 | 32 | 43 | |
| Chinese herbs | 23 | 20 | 3 |
an = 148
bn = 71
cn = 77