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. 2015 Apr 27;10(4):e0125454. doi: 10.1371/journal.pone.0125454

Fig 3. ALDH1high cells show enhanced chemoresistance.

Fig 3

The ALDH1high and ALDH1low cells of RD (A) and KYM-1 cells (B) were treated with 100 nM-10 μM vincristine, 5 mM-15 mM cyclophosphamide and 10 μM-100 μM etoposide and the cell viability was measured after 72 hours using a WST-8 assay. The viability of the “no treatment” cells was also measured as a control. The mean ± SD was calculated from triplicate wells of a representative experiment, and the data for three independent experiments are shown in the figure. The viability of the ALDH1high cells was significantly higher than that of the ALDH1low cells.