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. Author manuscript; available in PMC: 2016 Oct 1.
Published in final edited form as: Alzheimer Dis Assoc Disord. 2015 Oct-Dec;29(4):312–316. doi: 10.1097/WAD.0000000000000066

Table 2.

Clinical performance of cognitive screening tools for predicting delirium

Tool RR (95% CI) Sn (95% CI) Sp (95% CI) LR+ (95% CI) LR− (95% CI)
D=(MC)2 ≥2 2.5 (1.2, 5.5) 0.30 (0.12, 0.49) 0.88 (0.82, 0.93) 2.5 (1.2, 5.3) 0.79 (0.60, 0.94)
AD8 ≥2 2.4 (1.1, 5.1) 0.39 (0.19, 0.59) 0.82 (0.76, 0.88) 2.2 (1.2, 4.1) 0.74 (0.53, 0.90)
MMSE ≤24 5.5 (2.7, 11.1) 0.52 (0.32, 0.73) 0.89 (0.84, 0.94) 4.8 (2.6, 9.0) 0.54 (0.35, 0.76)
Mini-cog ≤2 2.7 (1.3, 5.7) 0.52 (0.32, 0.73) 0.75 (0.68, 0.82) 2.1 (1.3, 3.4) 0.64 (0.41, 0.82)
MMSE ≤24 AND D=(MC)2 ≥2 4.1 (1.8, 9.1) 0.17 (0.02, 0.33) 0.97 (0.94, 1.00) 6.0 (1.6, 22.5) 0.85 (0.70, 0.97)
MMSE ≤24 AND AD8 ≥2 2.7 (1.2, 6.3) 0.22 (0.05, 0.39) 0.93 (0.89, 0.97) 3.0 (1.1, 8.0) 0.84 (0.68, 0.96)
MMSE ≤24 OR D=(MC)2 ≥2 5.2 (2.4, 11.4) 0.65 (0.46, 0.85) 0.80 (0.73, 0.87) 3.2 (2.1, 5.1) 0.44 (0.25, 0.62)
MMSE ≤24 OR AD8 ≥2 5.8 (2.5, 13.1) 0.70 (0.51, 0.88) 0.78 (0.72, 0.85) 3.2 (2.1, 4.9) 0.39 (0.21, 0.55)

Sn = Sensitivity; Sp = Specificity; LR+ = positive likelihood ratio; LR− = negative likelihood ratio; RR = relative risk; CI = Confidence Interval