Figure 2.
Localization of extracellular matrix–degrading proteases in human cancer. Compilation of expression localization data for MMP-1, MMP-2, MMP-13, MMP-14, and uPA obtained from 291 published studies of human breast, colon, lung, and prostate cancer (supplemental text). The bar graphs show the number of studies reporting the expression of any of the proteases in stromal cells only, both cancer and stromal cells, and cancer cells only.