Table 1.
Ref. | Year | No. of patients | Proportion with HCV genotype 1 (%) | Treatment | SVR (%) | Dropout (%) |
Tan et al[85] | 2001 | 5 | NA | IFN-3.0 MU/d to 3 times/wk + RBV 200 mg/d, 3 times/wk for 40 wk | NA | 40 |
Mousa et al[86] | 2004 | 20 | 60-66 | IFN-3.0 MU/d to 3 times/wk + RBV 200 mg/d, 3 times/wk | ||
For 24 wk | 66 | 0 | ||||
For 48 wk | 55 | 0 | ||||
Bruchfeld et al[87] | 2006 | 6 | 66 | PegIFN - 50 μg/wk + RBV 200-400 mg/d for 24-48 wk (depending on genotype) | 50 | 50 |
Rendina et al[88] | 2007 | 35 | 45.7 | PegIFN-α2a 135 μg/wk + RBV 200 mg/d for 24-48 wk (depending on genotype) | 97 | 15 |
IFN: İnterferon; NA: Not available; PegIFN: Pegylated IFN; RBV: Ribavirin; SVR: Sustained virological response; HCV: Hepatitis C virus.