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. 2014 Nov 4;2014(50):346–358. doi: 10.1093/jncimonographs/lgu041

Table 2.

List of interventions and clinical outcomes of interest

Intervention
 Acupuncture
 Creative therapies
 Hypnosis
 Imagery/relaxation
 Meditation
 Mind-body practices
 Natural products (eg, botanicals, vitamins, minerals)
 Stress management
 Tai Chi/qigong
 Yoga
 Whole systems*
Clinical outcomes of interest (in alphabetical order)
 Fatigue**
 Gastrointestinal**
 Gynecological
 Hematological
 Lymphedema**
 Neurological**
 Neuromuscular**
 Pain**
 Psychological**
 Quality of life**
 Renal
 Skin**
 Sleep**
 Vasomotor symptoms**

* Whole systems are defined as an approach to health care in which practitioners apply bodies of knowledge and associated practices to maximize the patients’ capacity to achieve mental and physical balance and restore their own health, using individualized, nonreductionist approaches to diagnosis and treatment. In whole systems, the practitioner–patient relationship plays an important role and continues to evolve over time (28).

** Indicates where Grades A, B, C, D, and H recommendations are made in these guidelines, based upon quality of evidence.