Fig. 1.

Effect of RGS-insensitive Gα_i2^G184S/+ mutation on survival of DCM mice. Kaplan–Meier survival curves in a males and b females for Gα_i2^+/+ (WT); Gα_i2^G184S/+; TG9⁺Gα_i2^+/+ (DCM); TG9⁺Gα_i2^G184S/+ (DCM/Gα_i2^G184S/+) were compared by log-rank (Mantel–Cox) test. ***p<0.001 compared to respective TG9-control. ^†p<0.05; ^†††p<0.001 compared to respective Gα_i2^+/+control. n=9–13. Arrows indicate the time at which tissues were collected in subsequent studies