Fig. 5.
Expression of hypertrophy-associated genes. Real-time RT-PCR was performed on extracts of ventricular muscle from WT or Gαi2G184S/G184S mice after 7 days of saline or Iso treatment. Expression was normalized to β-actin. a Atrial natriuretic peptide (ANP), b brain natriuretic peptide (BNP), c type III collagen (Col III), and d smooth muscle actin (SMA). Values are mean±SEM, n=6 in each group. *p<0.05 and ***p<0.001 Iso- vs saline-treated animals. †p<0.05 and †††p<0.001, Gαi2G184S/G184S vs WT animals