Fig. 7.

Gα_i2-dependent cardiac fibroblast proliferation. Cardiac fibro-blasts from wild-type (WT) and RGS-insensitive Gα_i2^G184S/G184S hearts were grown for 3 days in 10% FBS without (PTX-) or with (PTX+) PTX. a DIC micrographs of cells. b Cell number was determined as described in “Methods.” Values are mean±SEM for three different animals with each assay done in duplicate. ^†p<0.05 Gα_i2^G184S/G184S vs WT cells *p<0.05 or ***p<0.001 for the effect of PTX