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. Author manuscript; available in PMC: 2015 Apr 28.
Published in final edited form as: Naunyn Schmiedebergs Arch Pharmacol. 2012 Mar 14;385(5):443–453. doi: 10.1007/s00210-011-0705-z

Table 1.

Effect of RGS-insensitive Gαi2 mutation (Gαi2G184S/+) on average age day of death in mice with cardiac-specific overexpression of Cre (TG9+)

i2+/+ i2G184S/+ TG9+i2+/+ TG9+ Gαi2G184S/+
Male ND ND 86.7±1.3 (n = 11) 82.9±1.1* (n=9)
Female ND ND 81.2±0.5 (n = 13) 76.7±0.5**(n=12)

Values are mean±standard error of the mean, n represents animals in each group (9–13). Differences were determined by Mantel–Cox log rank test from the survival curve analysis

ND none died up to 95 days

*

p<0.05

**

p<0.001, indicate a significant effect on survival as compared to respective Gαi2+/+ control