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Damaging and tolerated variant sets
| Damaging (HGMD) | Tolerated (1TGP + ESP) | |
|---|---|---|
| # initial variants | 176523 | 65377 |
| - # SYN | 1333 | 36546 |
| - # FR/SC/SD | 77627 | 929 |
| # final variants | 97653 | 27902 |
Damaging and tolerated sets after synonymous-SNVs and frameshift, stop-causing and stop-disrupting variants removal. An instance of the data set is the coding variant relative to the transcript to which overlaps. SYN = synonymous, FR = frameshift, SC = stop-causing, SD = stop-disrupting.
