Table 2.
Age of onset in years, adjusted HR analysis for overall survival rates in patients with pemphigus foliaceus
| Characteristic | No (%) | Deaths | HR (95% CI) | p-value |
|---|---|---|---|---|
| No (%) | ||||
| Age of onset ≥65 years | 7 (31.8%) | 4 (80.0%) | 13.48 (1.49 – 121.94) | 0.021 |
| Age of onset <65 years | 15 (68.2%) | 1 (20.0%) | ||
| Gender (M) | 4 (18.2%) | 0 (0.0%) | NA | NA |
| Gender (F) | 18 (81.8%) | 5 (100.0%) | ||
| Alcohol (Yes) | 2 (9.1%) | 0 (0.0%) | NA | NA |
| Alcohol (No) | 20 (90.9%) | 5 (100.0%) | ||
| Smoking (Yes) | 9 (40.9%) | 0 (0.0%) | NA | NA |
| Smoking (No) | 13 (59.1%) | 5 (100.0%) | ||
| High blood pressure (Yes) | 6 (27.3%) | 2 (40.0%) | 0.58 (0.09 – 3.80) | 0.570 |
| High blood pressure (No) | 16 (72.7%) | 3 (60.0%) | ||
| Coronary heart disease (Yes) | 3 (13.6%) | 1 (20.0%) | 3.07 (0.26 – 36.36) | 0.375 |
| Coronary heart disease (No) | 19 (86.4%) | 4 (80.0%) | ||
| Diabetes mellitus (Yes) | 2 (9.1%) | 1 (20.0%) | 7.79 (0.54 – 111.18) | 0.130 |
| Diabetes mellitus (No) | 20 (90.9%) | 4 (80.0%) | ||
| Dental problems (Yes) | 12 (54.5%) | 2 (40.0%) | 1.77 (0.24 – 13.24) | 0.579 |
| Dental problems (No) | 10 (45.5%) | 3 (60.0%) | ||
| ESR ≥ 30 mm/hour | 7 (31.8%) | 2 (40.0%) | NA | NA |
| ESR < 30 mm/hour | 5 (22.7%) | 0 (0.0%) | ||
| Steroids ≥ 1mg/kg/day | 4 (18.2%) | 1 (20.0%) | NA | NA |
| Steroids < 1 mg/kg/day | 12 (54.5%) | 2 (40.0%) | ||
| Anti-Dsg1 autoAbs ≥ 100 U/mL | 12 (54.5%) | 4 (80.0%) | 2.59 (0.28 – 24.13) | 0.404 |
| Anti-Dsg1 autoAbs < 100 U/mL | 10 (45.5%) | 1 (20.0%) |