Table 2.
Baseline characteristics of the study patients according to survival a
| Survivors, N =13,654 | Dead, N =2,164 | P -value | |
|---|---|---|---|
| Age, yr | 63 (50–73) | 67 (55–76) | <0.001 |
| Male sex | 65% (8827) | 63% (1372) | 0.26 |
| APACHE II score | 15.46 (5.78) | 26.15 (8.13) | <0.001 |
| SAPS II score | 26.9 (20.6) | 45.5 (26.1)) | <0.001 |
| Hospital A | 21% (2870) | 15% (335) | <0.001 |
| Hospital B | 11% (1474) | 11% (244) | 0.5 |
| Hospital C | 10%(1300) | 14% (307) | <0.001 |
| Hospital D | 59%(8010) | 59% (1278) | 0.73 |
| Mechanical ventilationb | 71% (9694) | 84% (1819) | <0.001 |
| Acute renal failurec | 71% (9694) | 84% (1819) | <0.001 |
| Surgical admissionsd | 4% (572) | 17% (362) | <0.001 |
| Elective surgery | 69% (9398) | 28% (596) | <0.001 |
| Infection as admission diagnosise | 55% (7507) | 9% (200) | <0.001 |
| Number of temperature measurements | 8% (1027) | 18% (392) | <0.001 |
| Mean temperature, °C | 36.7 (0.6) | 36.6 (1.0) | <0.001 |
| Highest temperature, °C | 37.6 (0.9) | 37.9 (1.4) | <0.001 |
| Lowest temperature, °C | 35.5 (2.1) | 34.9 (2.6) | <0.001 |
| SD of temperature, °C | 0.60 (0.45) | 0.78 (0.49) | <0.001 |
| Temperature >38°Cf | 26% (3469) | 45% (928) | <0.001 |
| Temperature >38.3°Cf | 18% (2441) | 36% (771) | <0.001 |
| Temperature >38.5°Cf | 13% (1812) | 30% (644) | <0.001 |
| Temperature >39°Cf | 6% (859) | 18% (388) | <0.001 |
| Temperature <35°Cf | 35% (4823) | 52% (1126) | <0.001 |
| Number of patients given paracetamol | 66% (9050) | 46% (996) | <0.001 |
| Total dose, g | 0 (0–0) | 3 (2–7) | <0.001 |
| Mean daily dose,g g | 0 (0–0) | 1.9 (1.0-2.6) | <0.001 |
aAPACHE, Acute Physiology and Chronic Health Evaluation; SAPS, Simplified Acute Physiology Score; SD, Standard deviation; bMechanical ventilation within first 24 hours of ICU admission; c24 hour urine output is <410 ml AND creatinine >133 μmol/L AND patient is not receiving chronic dialysis. dAPACHE III-J principal postoperative diagnosis. eA list of admission diagnosis with infection is provided in Additional file 1. fIndicates the presence of a given temperature at any time during intensive care unit stay. gMean daily dose calculated by dividing total dose by number by treatment days.