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. 2015 Apr 28;15:8. doi: 10.1186/s12900-015-0035-3

Figure 3.

Figure 3

Location of highly variable loop region in the 3CLpro of HKU1 (3D23). Colouring of backbone elements by B-factor indicates the presence of a highly variable loop from residues Ser46 to Asp53. This variable loop region may be responsible for the spike in DOPE score for 3D23, for which OC43 3CLpro has assumed a more stable conformation.