Table 2.
Characteristics of the study participants with follicular lymphoma in the Scandinavian Lymphoma Etiology (SCALE) study (Denmark/Sweden) and in the University of California San Francisco (UCSF) study
SCALE overall N (%) | Swedish FL cases N (%) | Danish FL cases N (%) | UCSF FL cases N (%) | |
---|---|---|---|---|
Number of participants | 373 | 231 (62) | 142 (38) | 213 |
Sex (men) | 185 (50) | 111 (48) | 74 (52) | 110 (52) |
Age (years) | ||||
18-34 | 9 (2) | 6 (3) | 2 (1) | 3 (1) |
35-44 | 30 (8) | 15 (6) | 13 (9) | 15 (7) |
45-54 | 105 (27) | 58 (25) | 43 (30) | 50 (23) |
55-64 | 139 (36) | 83 (36) | 53 (37) | 73 (34) |
65-75 | 100 (26) | 69 (30) | 31 (22) | 42 (20) |
76-84 | - | - | - | 30 (14) |
Median (range) | 57 (22–74) | 58 (22–74) | 56 (33–72) | 60 (29–84) |
Participant born in Sweden or Denmark (yes) | 342 (92) | 203 (88) | 139 (98) | - |
Parents born in Sweden or Denmark (yes) | 331 (89) | 193 (84) | 138 (97) | - |
Participants of European ancestry B | - | - | - | 213 (100) |
Ann Arbor stage | ||||
I | 77 (22) | 50 (23) | 27 (19) | - |
II | 48 (13) | 32 (15) | 16 (12) | - |
III | 100 (28) | 69 (32) | 31 (22) | - |
IV | 133 (37) | 68 (31) | 65 (47) | - |
Missing | 15 | 13 | 2 | - |
FLIPI A | ||||
Low risk | 136 (36) | 107 (46) | 29 (20) | - |
Intermediate risk | 152 (41) | 68 (29) | 84 (59) | - |
High risk | 85 (23) | 56 (24) | 29 (20) | - |
Progression (yes) | - | 155 (67) | - | - |
Missing | - | 2 (1) | - | - |
Transformation (yes) | - | 56 (26) | - | - |
Missing | - | 12 (5) | - | - |
Rituximab first line/any treatment line (yes) | - | 24 (10)/106 (47) | - | - |
Missing | - | 5 (2) | - | - |
Died | 137 (37) | 88 (38) | 49 (35) | 56 (26) |
Died due to lymphoma | 88 (24) | 54 (23) | 34 (24) | 24 (11) |
AThe Swedish patients were classified according to the number of FLIPI risk factors. The Danish patients were classified according to a modified FLIPI, based on age and stage only.
BNon-European samples according to MDS plot inspection were removed in UCSF.