Table 3.
Polymorphism association with for four different models including Full genotype, Dominant, Recessive, and Multiplicative (for alleles)
| Model | Genotype | Group 1 n (%) | Group 2 n (%) | Group 3 n (%) | P-value | Group 1 vs. Group 2 | Group 1 vs. Group 3 | ||
|---|---|---|---|---|---|---|---|---|---|
| OR (95% CI) | AIC | OR (95% CI) | AIC | ||||||
| Full genotype | G/G | 8. (7.3) | 11. (14.9) | 24. (21.2) | < 0.001 | 1.00 | 235.22 | 1.00 | 302.81 |
| A/G | 102. (92.7) | 55. (74.3) | 87. (77.0) | 2.55 (0.97-6.71) | 3.52 (1.50-8.23) | ||||
| A/A* | 0 | 8. (10.8) | 2. (1.8) | *- | *- | ||||
| Dominant | G/G | 8. (7.3) | 11. (14.9) | 24. (21.2) | 0.012 | 1.00 | 249.30 | 1.00 | 303.89 |
| A/G+A/A | 102. (92.7) | 63. (85.1) | 89. (78.8) | 2.23 (0.85-5.83) | 3.44 (1.47-8.04) | ||||
| Recessive | G/G+A/G | 110. (100) | 66. (89.2) | 111. (98.2) | < 0.001 | 1.00 | - | 1.00 | - |
| A/A* | 0 | 8. (10.8) | 2. (1.8) | *- | *- | ||||
| Multiplicative | G | 53. (48.2) | 27. (36.5) | 44. (38.9) | 0.214 | 1.00 | 499.89 | 1.00 | 620.52 |
| A | 57. (51.8) | 47. (63.5) | 69. (61.1) | 0.94 (0.62-1.42) | 1.29 (0.88-1.87) | ||||
Group1: patients who are seropositive, Group2: seropositive healthy controls, Group3: seronegative healthy controls *Computing OR (95% CI) was not possible because of small sample size.