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. Author manuscript; available in PMC: 2015 Apr 28.
Published in final edited form as: Int J Biostat. 2014;10(2):185–196. doi: 10.1515/ijb-2014-0015

Table 1.

Optimal design strategy based on a binary outcome

p0 = 0.10 and p1 = 0.20
p0 = 0.10 and p1 = 0.30
ρ = 0 ρ = 0.2 ρ = 0.4 ρ = 0 ρ = 0.2 ρ = 0.4
Optimal proportions of siblings and singletons pe = 57% pe = 7% pe = 0% pe = 60% pe = 15% pe = 8%
pc = 43% pc = 0% pc = 0% pc = 40% pc = 0% pc = 0%
pec = 0% pec = 93% pec = 100% pec = 0% pec = 85% pec = 92%