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. Author manuscript; available in PMC: 2016 Jan 5.
Published in final edited form as: Eur J Pharmacol. 2014 Oct 30;746:106–114. doi: 10.1016/j.ejphar.2014.10.042

Fig 4. Arginase Activity and Arginase 1 Expression in BAECs.

Fig 4

BAECs were transfected with either siRNA for ATF-2, c-Jun or scrambled (SC) siRNA. BAECs were then treated with Ang II (0.1 µM, 24h) (A) Elevation of arginase activity by exposure of BAECs to Ang II was prevented by transfection of cells with ATF-2 siRNA and partially prevented by c-Jun transfection. Transfection with sc-siRNA did not prevent response to Ang II. n= 3 *P<0.05 vs. control, #P<0.05 vs. SC siRNA for Ang II. (B) Elevation of arginase 1 expression by exposure of BAECs to Ang II (0.1 µM, 24 h) was prevented by transfection of cells with ATF-2 siRNA. Transfection with sc-siRNA did not prevent response to Ang II. Values are expressed as means of percent of control ± S.E.M..n= 3. *P<0.05 vs. control, #P<0.05 vs. SC siRNA for Ang II.