Table 5.
Relative final fluorescence (RFF) based on accumulation of EtBr.
Strains | RFF of the efflux inhibitors | |||||
---|---|---|---|---|---|---|
Verapamil | Thioridazine | Chlorpromazine | ||||
− glucose | + glucose | − glucose | + glucose | − glucose | + glucose | |
FURG-1 | 0.82 | 0.47 | 0.66 | 0.29 | 0.32 | 0.01 |
FURG-2 | 1.36 | 1.01 | 0.63 | 0.33 | 0.39 | 0.21 |
FURG-3 | 0.71 | 0.53 | 0.21 | 0.27 | 0.07 | −0.04 |
FURG-4 | 1.58 | 1.22 | 0.76 | 0.45 | 0.64 | 0.46 |
FURG-5 | 1.62 | 1.48 | 1.37 | 1.54 | 1.06 | 1.01 |
H37Rv | 1.57 | 2.27 | 0.77 | 1.31 | 0.52 | 0.88 |
Accumulation of EtBr at 0.25 μg/ml (H37Rv), 0.5 μg/ml (FURG-2 to 5), and 1 μg/ml (FURG-1), in the presence of glucose at 0.4%. The most efficient inhibitors are in bold type.