Table 2.

CAR constructs utilized in PB-NK cells.

Reference	Target	CAR construct	Method
(37)	CD19	CD8α TM/CD3ζ	Retrovirus (mean 69%)
		CD8α TM/DAP10
		CD8α TM/CD137/CD3ζ
(40)	ErbB2 (HER-2)	CD28/CD3ζ	Retrovirus (mean 55%)
(38)	CD19/GD2	CD3ζ or 2B4 alone	Retrovirus (13–24%)
		2B4/CD3ζ
		CD8 TM/CD137/CD3ζ
(39)	CD19	CD137/CD3ζ	Transfection (mRNA) (mean 58%)
(42)	NKG2D ligands	NKG2D/CD3ζ co-expressed with DAP10	Retrovirus and mRNA transfection
(41)	ErbB2 (HER-2)	CD3ζ alone	Retrovirus (40–50%)
		CD28/CD3ζ
(33)	CD20	CD137/CD3ζ	Transfection (mRNA) (50–95%)