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. 2014 Sep 20;17(9):649–655. doi: 10.3779/j.issn.1009-3419.2014.09.02

3.

Hazard ratios (95%CI) for lung cancer according to average sleep duration in Physicians' Health Study

Sleep duration (h) Cases/personyears Crude incidence rate (per 1, 000 person-yrs) Hazards ratio (95%CI)
Unadjusted Model 1 Model 2
Model 1: Age (< 60, 60- < 65, 65- < 70, 70- < 75, 75+) and race (white/non-white).
Model 2: Age (< 60, 60- < 65, 65- < 70, 70- < 75, 75+), race (white/non-white), parental history of cancer (yes/no), exercise frequency (Never/Rarely, 1-3/mo, 1-4/wk, 5-7/wk), caloric intake (tertiles), body mass index (continuous), type 2 diabetes (yes/no), alcohol consumption (< 1/wk, 1-4/ wk, 5-7/wk, > 7/wk), smoking status (never, past, current), sleep apnea (yes/no), and snoring (mostly/always, few/occasionally, rarely/never, unknown/missing), alcohol consumption (< 1/wk, 1-4/wk, 5-7/wk, > 7/wk), smoking status (never, past, current), sleep apnea (yes/no), and snoring (mostly/always, few/occasionally, rarely/never, unknown/missing).
≤6.0 35/40, 582 0.86 1.08 (0.71-1.66) 1.25 (0.82-1.92) 1.18 (0.77-1.82)
7.0 53/66, 352 0.80 1.0 1.0 1.0
≥8.0 62/51, 345 1.21 1.52 (1.05-2.19) 1.11 (0.76-1.60) 0.97 (0.67-1.41)
P for quadratic trend 0.155 0.348 0.697