Table 1. Distribution of alternative sequences in the four types of H. pylori CagA TPMs^a.

	Number
TPM type	Total	EPIYA	EPIYT	ESIYA	ESIYT	Other
	(n = 7954)	(n = 7207) (%)	(n = 478)	(n = 96)	(n = 60)	(n = 113)
A	2521	2517 (99.8)	4	0	0	0
Bb	2617	1899 (72.6)	474	96	60	88c
C	1620	1595 (98.5)	0	0	0	25d
D	1196	1196 (100)	0	0	0	0

^a From review of Genbank entries to Aug. 8, 2013.

^bB-TPM bolded, since most variable.

^c B-domain other TPMs include: GSIYD (31), EPVYA (13), ELIYA (12), ESIYD (7), ETIYA (3), EPIYD (3), EHIYA (2), EPTYA (2), EPIYS (2), EPIYV (2), ESVYA (2), DPIYA (1), DPIYD (1), EPVYT (1), QPIYP (1), EPIFT (1), EPIHA (1), EPINA (1), ESIYS (1), EFIYT (1).

^d The C-domain other TPMs all are EPIYV (25), which only is present when the B-domain sequence is GSIYD (p<0.0001).