Table 3. Relation of B-domain TPM sequence type to number of C-domain TPMs in 1322 Western CagA sequences.
B-TPM Sequence type | Totala | C-TPM number (%) | |||
---|---|---|---|---|---|
(n = 1322) | 1 (n = 1035) | 2 (n = 254) | 3 (n = 33) | p-value | |
EPIYA | 730 | 582(79.7) | 124(17.0) | 24(3.3) | NSb |
EPIYT | 436 | 339(77.8) | 90(20.6) | 7 (1.6) | NS |
ESIYA | 26 | 21 (80.8) | 4(15.4) | 1 (3.8) | NS |
ESIYT | 50 | 14 (28.0) | 35(70.0) | 1 (2.0) | <0.001 |
Others | 80 | 79 (98.8) | 1 (1.2) | 0 (0.0) | NS |
a For some Western strains (n = 16), there are > 3 C-TPMs.
b NS, P>0.05.