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. Author manuscript; available in PMC: 2016 Apr 1.
Published in final edited form as: Psychopharmacology (Berl). 2014 Oct 25;232(8):1415–1426. doi: 10.1007/s00213-014-3777-x

Table 3.

Effect of bilateral intra-nucleus accumbens shell THIP infusions on bout parameters for limited-access consumption of 10% ethanol (10E)

Dose THIP 0 ng 100 ng 500 ng
2-hr 10E licks 668 ± 70 587 ± 139 502 ± 161
22-hr water intake (ml) 3.2 ± 0.4 2.6 ± 0.5 3.8 ± 0.2
Total fluid intake (ml) 3.9 ± 0.3 3.1 ± 0.6 4.1 ± 0.3
Average bout size (licks) 98 ± 7 104 ± 15 105 ± 22
Latency to first lick (minutes) 24.8 ± 6 19.3 ± 8 8.7 ± 4
Latency to first bout (minutes) 25.0 ± 7 20.7 ± 8 11.5 ± 5
First bout size (licks) 93 ± 16 101 ± 23 71 ± 13
Termination of last bout (minutes) 115 ± 1 83 ± 7 102 ± 14

Values represent mean ± SEM for each dose. 0 ng represents the average of the pre and post vehicle infusion.