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. Author manuscript; available in PMC: 2015 Apr 28.
Published in final edited form as: J Comp Neurol. 2008 Sep 20;510(3):237–250. doi: 10.1002/cne.21746

Fig. 2.

Fig. 2

Sox9 and Sox2 are coexpressed in multipotent retinal progenitor cells. Retinae from the indicated developmental stages were colabeled with antibodies against Sox9 and Sox2. At E12.5, Sox9 and Sox2 are expressed throughout the RPCs (A–F) and the developing optic nerve (C, arrowhead) while Sox9 is expressed distinctively in the retinal pigment epithelium (arrowheads in F). By E14.5, Sox9, and Sox2 are coexpressed at comparable levels in the RPCs (J–L). At E16.5, discrete Sox2 +, but Sox9-negative cells appear within the vitreal side of the retina (M–O, arrows). R, retina; L, lens; onbl, outer neuroblastic layer; inbl, inner neuroblastic layer; INL, inner nuclear layer; GCL, ganglion cell layer. N = 3 mice per timepoint. Scale bars = 50 µm.