Table 3.
Number matrix of root mean square fluctuation (RMSF) for wild-type BRAF alone (apo), BRAF(V600E) alone (M-apo), and the corresponding BRAF(V600E) protein for aknadicine (top1), 16beta-hydroxy-19s-vindolinine N-oxide (top2), and the control (SB-590885)
| Apo | M-apo | Top1 | Top2 | Control | |
|---|---|---|---|---|---|
| Apo | 1 | 0.1225 | 0.1158 | 0.13 | 0.1113 |
| M-apo | 0.1225 | 1 | 0.8192 | 0.7798 | 0.7117 |
| Top1 | 0.1158 | 0.8192 | 1 | 0.8021 | 0.7049 |
| Top2 | 0.13 | 0.7798 | 0.8021 | 1 | 0.7442 |
| Control | 0.1113 | 0.7117 | 0.7049 | 0.7442 | 1 |
Note: The number “1” means the highest similarity when we compare two proteins.
Abbreviation: M-apo, mutated apo.