Table 2.

Mean connectivity z-scores between the left insular seed and functionally connected brain structures in the happy-sad contrast in the depressed group (MDD) and healthy controls (HCL).

Structure	Hemisphere	Volume (μL)	Center of mass			Average F valuea	Mean connectivity z-score
			X	Y	Z		MDD	HCL
Happy-sad Contrast: L Insula Seed
Declive	L	14,040	20	60	−19	5.93	0.02	−0.01
Fusiform Gyrus	R	13,797	−28	56	−13	6.18	0.02	−0.02
Middle Frontal Gyrus	L	13,068	42	−18	30	6.19	0.02	−0.01
Precuneus	L	5,994	12	76	37	5.85	0.02	−0.01
Culmen	R	5,373	−3	41	−28	6.57	0.02	−0.01
Inferior Parietal Lobule	L	3,672	58	41	26	5.98	0.02	−0.02
Precuneus	R	2,997	−18	67	25	5.43	0.02	−0.02
Amygdala/Parahippocampal Gyrus	R	2,538	−29	1	−29	6.15	0.02	−0.02
Cingulate Gyrus	L	2,322	12	16	35	7.00	0.02	−0.02
Precuneus	R	2,160	−21	81	41	6.00	0.02	−0.01

^aF_{(1, 65)}