Table 3.
Reasons for death or graft failure in SLKT recipients with either preformed or de novo class II DSA (MFI > 2000) versus those without DSA (p = 0.01).
| Class II DSA | No DSA | |
|---|---|---|
| Alive | 31% | 60% |
| Liver allograft failure1 | 31% | 4% |
| Renal failure | 11% | 6% |
| Cancer/infection/other | 27% | 28% |
| Unknown | 0% | 2% |
1
Liver allograft failure was found in 8 patients with class II DSA: 2 with primary graft nonfunction, 2 with acute or chronic rejection, 2 with biliary causes, and 1 with recurrent hepatitis C. Two patients died from liver allograft failure without class II DSA: one from recurrent hepatitis C and one from recurrent hepatitis B with vascular thrombosis.