Fig. 3.

Schematic showing the 3′UTR fragments of the BDNF mRNA that were used to study BDNF–miR interactions. Only studies in which the size of the 3′UTR fragment was reported are included. The binding sites for the miRs examined in each study are shown in red. The alternative transcription stops and polyadenylation sites that yield two distinct BDNF mRNA isoforms (i.e., containing a short and long 3′UTR) are indicated with red arrows. NM_170735.5 refers to human BDNF mRNA, transcript variant 1, NCBI reference sequence. H human 3′UTR, M mouse 3′UTR, R rat 3′UTR, Asterisk miR-binding site present only in humans