Table 2.
Clinical characteristics of study cohorts
| Variable | CEASAR | PCOS | p value |
|---|---|---|---|
| PSA | |||
| Mean | 6.7 | 9.6 | <0.001 |
| Median | 5.3 (4.1–7.3) | 7.3 (5.2–11.3) | |
| Gleason score, % (n) | |||
| ≤6 | 41 (1297) | 43 (1014) | <0.001 |
| 7 | 28 (887) | 16 (369) | |
| 8–10 | 8 (254) | 6 (145) | |
| Missing | 22 (697) | 35 (805) | |
| Treatment, % (n) | <0.001 | ||
| Surgery | 51 (1592) | 58 (1344) | |
| Radiation | 27 (849) | 25 (586) | |
| Active surveillance | 11 (346) | 12 (275) | |
| Hormone therapy | 2 (75) | 6 (129) | |
| Other | 9 (273) | 0 (0) | |
| No. of comorbidities, %(n) | <0.001 | ||
| 0 | 43 (1337) | 40 (932) | |
| 1 | 36 (1122) | 31 (732) | |
| 2 | 15 (464) | 16 (376) | |
| ≥3 | 7 (212) | 13 (294) | |
| Self-reported overall health, % (n) | 0.017 | ||
| Excellent | 19 (603) | 19 (450) | |
| Very good | 38 (1186) | 37 (850) | |
| Good | 31 (966) | 30 (699) | |
| Fair | 10 (299) | 11 (261) | |
| Poor | 2 (74) | 2.3 (54) | |
| Hypertension, % (n) | 50 (1561) | 34 (805) | <0.001 |
| Heart failure, % (n) | 3 (98) | 5 (121) | <0.001 |
| Stroke, % (n) | 3 (93) | 4 (103) | 0.001 |
| Heart attack, % (n) | 6 (217) | 7 (161) | 0.499 |
| Angina, % (n) | 3 (111) | 7 (168) | <0.001 |
| Diabetes mellitus, % (n) | 15 (500) | 14 (323) | 0.285 |
| Colitis, % (n) | 2 (60) | 4 (90) | <0.001 |
CAESAR = Comparative Effectiveness Analysis of Surgery and Radiation; PCOS = Prostate Cancer Outcomes Study; PSA = prostate-specific antigen.
Percentages may not add to 100% due to rounding.