(A) Mean changes in TER of HUVEC (A), HCMEC (B), and HDMEC (C) pretreated with 10 μM JNJ or vehicle for 30 minutes prior to stimulation with 10 μM histamine for 10 minutes. Values are means ± SE. *P<0.001 versus control. †P<0.001 versus all other groups. For all HUVEC groups, n=8; for all HCMEC groups, n=4; for all HDMEC groups, n=16.