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. 2015 Apr 15;5:335–340. doi: 10.1016/j.fob.2015.04.006

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© 2015 The Authors

This is an open access article under the CC BY-NC-ND license (http://creativecommons.org/licenses/by-nc-nd/4.0/).

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Fig. 5 — Olanzapine inhibition of glucose transport by N136A, R367A and wild-type GlcP_Se. Wild-type and N136A GlcP_Se RSO vesicles or R367A GlcP_Se cells were pre-incubated with different concentrations of olanzapine for 1 min, before measuring glucose uptake. IC_50,wild-type = 0.9 ± 0.1 mM; IC₅₀,_N136A = 1.5 ± 0.2 mM; IC₅₀,_R367A = 0.8 ± 0.1 mM. Error bar is standard deviation from 3 different measurements.