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. 2015 Apr 29;35(17):6770–6785. doi: 10.1523/JNEUROSCI.4926-14.2015

Table 1.

Transgenic/mutant mice used in the studies

Strain name Strain description
Fcer1g-null Lack all activating but express inhibitory FcγRIIB
Fcgr2b-null Lack inhibitory FcγRIIB but express all activating FcγRs
Op/op mice Devoid of colony stimulating factor 1; are macrophage and microglia deficient
DBA mice Deficient in complement component C5
B4galnt1-null Lack beta1,4-N-acetylgalactos-aminyltransferase (GM2/GD2 synthase); express only simple gangliosides GM3 and GD3, but not complex gangliosides GM1, GD1a, GD1b, or GT1b

FcγRs = Fcγ receptors.