Table 1.
Result of body gain, HbA1c and lipid profile of study groups
| Parameters | Sham | Control | NTD | VETD |
|---|---|---|---|---|
| Body gain15 (g) | 2.00 ± 0.75 | 2.80 ± 0.68 | -18.25 ± 4.38* | -2.62 ± 2.70*† |
| Body gain30 (g) | 6.50 ± 0.82 | 6.50 ± 0.94 | -17.60 ± 4.20* | 9.00 ± 4.60† |
| Body gain42 (g) | 11.50 ± 1.47 | 11.37 ± 1.34 | -24.10 ± 5.90* | 6.25 ± 6.22† |
| HbA1c (%) | 9.38 ± 0.73 | 9.50 ± 0.55 | 29.80 ± 1.00 | 9.95 ± 0.85† |
| Cholesterol (mg/dl) | 48.40 ± 2.60 | 48.80 ± 1.90 | 70.58 ± 3.50* | 54.25 ± 2.70† |
| Triglyceride (mg/dl) | 30.85 ± 1.00 | 31.14 ± 0.96 | 53.28 ± 3.80* | 35.00 ± 3.10† |
| HDL (mg/dl) | 31.57 ± 1.60 | 30.70 ± 2.27 | 42.2.10 ± 2.10* | 36.00 ± 2.40 |
| LDL (mg/dl) | 27.70 ± 1.40 | 25.70 ± 2.30 | 36.00 ± 3.50* | 29.30 ± 2.20† |
| Apo-A (mg/l) | 138.50 ± 4.50 | 13.00 ± 8.20 | 93.80 ± 1.24* | 123.00 ± 2.07† |
| Apo-B/Apo-A | 0.86 ± 0.04 | 0.79 ± 0.040 | 1.70 ± 0.06* | 0.94 ± 0.30† |
| Blood glucose 48 h after STZ injection | 147.00 ± 2.60 | 148.00 ± 3.20 | 462.00 ± 24.70* | 44.00 ± 16.80* |
| Blood glucose at the end of experiment | 146.80 ± 2.90 | 150.00 ± 2.70 | 510.00 ± 12.90* | 283.00 ± 16.70*† |
Values are expressed as mean ± SEM.
*
Significant difference compared to control and sham.
†
Significant difference compare to the NTD (non-treated diabetic). VETD, vitamin E-treated diabetics; Apo, apoptosis; STZ, streptozocin