TABLE 1.

Rationale for vaccine development for nontypeable Haemophilus influenzae

Infection	Population to vaccinate	What vaccine will accomplish
Otitis media	All children beginning at 2 mo of age	Prevention of:
		Acute otitis media
		Recurrent otitis media
		Chronic otitis media
		Otitis media with effusion related to bacterial biofilm formation
		Chronic suppurative otitis media
		Reductions in:
		Excess antibiotic use
		Health care costs
Exacerbation of COPD	Adults with COPD	Prevention of:
		Acute exacerbations of COPD
		Chronic airway colonization
		Reductions in:
		Excess antibiotic use
		Health care costs